Anyone wishing to undergo fraxel laser treatments should first discuss any potential fraxel laser side effects in order to make an informed and responsible decision about whether to go through with the treatment. Like any procedure, fraxel laser treatments do sometimes have side effects, and it is up to the individual patient to decide whether or not the potential side effects are acceptable. Some may decide not to take the risk, while others may feel that the benefits of fraxel laser treatments outweigh the risks. Some general side effects related to fraxel lasers include swelling and redness. Skin may peel as if sunburned, and in some cases the swelling may be severe and uncomfortable.. Acne is also a common side effect of fraxel lasers.